







What to Expect With Wuffes
Here’s some helpful information on how to take Wuffes, and what to expect in the first 90 days of consistent use.
Configured by Pet Scientists
No artificial colors and flavors
Guaranteed results within 90 days
Complies with FDA CVM guidelines
GMP/SQF Certification
Configured by Pet Scientists
No artificial colors and flavors
Guaranteed results within 90 days
Complies with FDA CVM guidelines
GMP/SQF Certification
Configured by Pet Scientists
No artificial colors and flavors
Guaranteed results within 90 days
Complies with FDA CVM guidelines
GMP/SQF Certification
Configured by Pet Scientists
No artificial colors and flavors
Guaranteed results within 90 days
Complies with FDA CVM guidelines
GMP/SQF Certification
Configured by Pet Scientists
No artificial colors and flavors
Guaranteed results within 90 days
Complies with FDA CVM guidelines
GMP/SQF Certification
Configured by Pet Scientists
No artificial colors and flavors
Guaranteed results within 90 days
Complies with FDA CVM guidelines
GMP/SQF Certification
Configured by Pet Scientists
No artificial colors and flavors
Guaranteed results within 90 days
Complies with FDA CVM guidelines
GMP/SQF Certification
Configured by Pet Scientists
No artificial colors and flavors
Guaranteed results within 90 days
Complies with FDA CVM guidelines
GMP/SQF Certification
80% of dogs over 8 have joint problems
Based on scientific evidence, 20% of adult dogs (over 5) and 80% of dogs over 8 suffer from painful joint issues†. Our joint chews are filled with heavily studied active ingredients that help support joint flexibility and mobility.
Act now to enhance your pup’s joint health and maintain their mobility, well into their senior years
Data Doesn't Lie
Real results from real customers.
Our 4 Pillars of Joint Health
Our products work together to address every aspect of joint health, offering a comprehensive solution to keep your pet active, happy, and healthy.

1. Protect & Support
Choose between our Advanced Hip & Joint Support chews and Advanced Joint Liquid based on your pup’s preferences and levels of discomfort. They’re highly concentrated to protect and actively enhance bone & joint health.
Joint Chews are ideal for daily maintenance, while the Advanced Joint Liquid is for dogs needing more intensive joint care.

2. Nourish
OurAdvanced Omega 3 Fish Oilhelps relieve inflammation from exercise and aging, promoting the normal production and maintenance of synovial fluid. Rich in EPA and DHA, it nourishes the body with essential fatty acids that support cartilage health and synovial fluid production.

3. Soothe
CBD Isolate Oiltargets and eases joint stiffness by relieving inflammation from daily activity. CBD works at a cellular level to reduce inflammatory signals, providing your dog with much-needed alleviation from joint discomfort.

4. Restore
Ourlow-level light laserincreases blood flow to promote faster healing. The laser therapy stimulates blood flow, to promote faster healing.
Clinical Studies
Our chews are being clinically-studied with the largest number of participants ever in the joint health supplements for dogs space†. Full results coming soon!
†We’re performing a triple blind clinical trial of 120 client-owned dogs to examine the efficacy of our joint chews.
Crafted with Love, Backed By Science
Our scientifically-proven ingredients have been scrutinized in thousands of studies, and are meticulously selected for their combined effect to enhance joint health & mobility.
Collapsible content
The Research
The Research
Read more about the science behind our ingredients in our Ingredients Glossary
Full Ingredients
Full Ingredients
Active Ingredients
Glucosamine 1250mg, MSM 400mg, Green-Lipped Mussels 100mg, Chondroitin 150mg, Hyaluronic Acid 21mg, Vitamin C/Calcium Ascorbate 50mg, Omega 3s (from Wild Alaskan Salmon Oil) 16.5mg, Yucca Schidigera 10mg.
Inactive Ingredients
Apple Cider Vinegar, Brewer’s Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pork Spray Dried Liver, Tapioca Starch.
Real Results From Real Vets and Customers
The Proof is in the Progress
Watch Sadie’s 3 month transformation with Advanced Hip & Joint Support chews. Her dog dad Stephen used an activity tracker to monitor her steps and shared a month-by-month view of her journey.
Science vs Myth
Joint supplements are only for older dogs
Joint supplements are only for older dogs
The Truth:While it’s true that senior dogs benefit greatly from joint support, supplements like our Advanced Hip & Joint Support are beneficial at any age. Especially for large breeds or active dogs. Starting proactive joint care early can help support long-term health, so your pup can enjoy zoomies for years to come!
Supplements aren't as effective as prescription medications
Supplements aren't as effective as prescription medications
The Truth:Supplements including ingredients like Glucosamine, Chondroitin, MSM & Green Lipped Mussels, like our scientifically-formulated Advanced Hip & Joint Support, have been shown to help maintain joint health, reduce occasional discomfort, and support mobility. Our products work hand-in-hand with your vet’s recommendations, complementing any necessary treatments with holistic, well-researched ingredients.
Joint supplements replace the need for exercise and a healthy diet
Joint supplements replace the need for exercise and a healthy diet
The Truth:Our joint supplements are an important part of a holistic approach to your dog’s well-being, but they're not a magic fix! Regular exercise and a balanced diet are key to maintaining joint health and overall vitality. Think of our supplements as the boost your dog’s joints need to stay happy and active.
Joint supplements are just a trend
Joint supplements are just a trend
The Truth:Joint health supplements have been researched extensively. Ingredients like Glucosamine and Chondroitin are backed by scientific studies that show their potential to support cartilage health, reduce occasional joint discomfort, and help maintain mobility. They’re not just a trend - they’re part of a well-rounded care routine that can keep your dog moving comfortably.
FAQS
What are the full ingredients?
What are the full ingredients?
Active Ingredients
Glucosamine 1250mg, MSM 400mg, Green-Lipped Mussels 100mg, Chondroitin 150mg, Hyaluronic Acid 21mg, Vitamin C/Calcium Ascorbate 50mg, Omega 3s (from Wild Alaskan Salmon Oil) 16.5mg, Yucca Schidigera 10mg.
Inactive Ingredients
Apple Cider Vinegar, Brewer’s Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pork Spray Dried Liver, Tapioca Starch.
How can it benefit my pet?
How can it benefit my pet?
Our Advanced Hip and Joint chews harness the superpowers of Glucosamine, Chondroitin, Green-Lipped Mussels, Hyaluronic Acid and MSM to drive effective and visible results Our formula helps enhance joint health and improve discomfort from normal exercise and aging, helping maintain mobility. Our amazing chews can also be given to younger pups to help promote optimum bone and joint health.
They help:
- Support joint flexibility
- Maintain joint mobility
- Enhance healthy joint fluid viscosity
- Enhance tissue pliability
- Support the structural integrity of joints and connective tissues
- Provide bone-reinforcing factors
- Maintain a normal inflammatory response
- Ease aches and discomfort caused by exercise and normal aging
How should it be stored?
How should it be stored?
To make sure your pup is getting the absolute best, our joint chews do not contain artificial preservatives. Please store in a cool, dry place, out of direct sunlight and heat, and use within 3 months of opening.
Does it contain any allergens?
Does it contain any allergens?
In order to look out for as many pups as possible, we formulated our chews with allergies in mind. If your pet is particularly sensitive, please note that Advanced Hip & Joint Support includes Pork, Fish and Brewer’s Yeast (gluten).
Can my pet overdose?
Can my pet overdose?
If your pet devours an entire tub of Advanced Hip & Joint Support, they’ll be absolutely fine as long as the tub was designed for their weight category. Adverse effects can include vomiting, diarrhea, lethargy or gastrointestinal distress. If they’ve eaten more than one tub, or are experiencing symptoms for more than 24 hours, contact your vet for guidance.
Where is it made?
Where is it made?
Our products are proudly made in the USA from globally sourced ingredients.
Do pets need joint supplements?
Do pets need joint supplements?
Joint supplements are important because they help support and maintain joint health, particularly in aging dogs or those with specific joint-related issues. They can also be beneficial for younger pups, especially larger dogs and breeds that are prone to joint issues.
How do I know if my pet needs a joint supplement?
How do I know if my pet needs a joint supplement?
With 1 in 5 dogs developing joint issues in their lifetime (reference), it’s very important for pet parents to look out for and recognize signs of joint discomfort. Some signs to look out for include:
- Limping
- Difficulty stand up and/or lying down
- Shaking legs
- Uneven weight bearing and/or favoring one side
These are also very common signs of other issues. If your pet exhibits one or more of these, please consult your veterinarian.
Can it be used with other supplements or prescription medication?
Can it be used with other supplements or prescription medication?
Absolutely. As long as you follow our directions for use, our joint chews should not interfere with other supplements or prescription medications.
How old does my dog have to be?
How old does my dog have to be?
Advanced Hip & Joint Support is suitable for pets over 12 weeks of age.
Where can I find my account?
Where can I find my account?
All you have to do is click on the user icon on the top right of the page - right next to the shopping cart.
Where are your products made?
Where are your products made?
We’re proud to say all of our products are made in the USA with domestically and globally sourced ingredients.
How long do orders take to ship?
How long do orders take to ship?
All orders placed before noon are shipped on the same day, while all other orders will ship within 1 business day. Not to worry, we won’t keep you waiting!
How do I return an item?
How do I return an item?
If you’re not satisfied with your purchase, please emailhello@wuffes.comand our customer service will be happy to help.
Where are your products shipped from?
Where are your products shipped from?
All our products are made in the USA and shipped from our warehouse in Denver, Colorado.
Can I give Wuffes supplements to a pregnant dog?
Can I give Wuffes supplements to a pregnant dog?
Our products haven’t been tested on pregnant or lactating dogs so we recommend speaking to your vet beforehand.
The Research
The Research
- GLU/CHO Method of Action Review of studies, explains how glucosamine and arthritis work to treat and prevent arthritis
- GLU/CHO Improves OA GLU/CHO combination supplement significantly improves scores for pain, weight bearing and severity of condition in 70 days
- Oral GLU Supplementation Oral glucosamine reduced histological signs of OA in 8 weeks
- GLU/MSM Combination GLU/MSM combination significantly improves pain and swelling scores, more effective in combination than alone
- MSM OA Review MSM supplementation significantly improves OA-associated pain scores
- GLM & Canine Arthritis GLM improves pain and swelling scores, reduces total arthritis score in canine model
- GLM & Canine OA Pain GLM increases blood Omega 3s and reduces OA scores in 90 day
- Pain Study GLM reduces pain in 8 weeks in canine model
- Effects of Chondroitin Supplementation on OA (page 284-288)
- Vitamin C and Osteoarthritis (page 276)
- GLU/CHO Method of Action Review of studies, explains how glucosamine and arthritis work to treat and prevent arthritis
- GLU/CHO Improves OA GLU/CHO combination supplement significantly improves scores for pain, weight bearing and severity of condition in 70 days
- Hyaluronic Acid as Support for OA
- Fish Oil Supplementation Reduces Inflammatory Markers in Dogs with OA
- Omega 3 Supplementation Improves Mobility in Dogs with OA
- Omega 3 Supplementation Improves Clinical Signs of OA in Dogs
- Review on Yucca and Arthritis
- Anti-Inflammatory Properties of Yucca